Detalhe da pesquisa
1.
A cell-based functional assay that accurately links genotype to phenotype in familial HLH.
Blood
; 141(19): 2330-2342, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706356
2.
Filaggrin-Associated Atopic Skin, Eye, Airways, and Gut Disease, Modifying the Presentation of X-Linked Reticular Pigmentary Disorder (XLPDR).
J Clin Immunol
; 44(1): 38, 2024 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38165470
3.
Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick disease type C1.
Blood
; 139(12): 1833-1849, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35081253
4.
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.
Nature
; 549(7670): 101-105, 2017 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28813417
5.
Lipid specificity of the immune effector perforin.
Faraday Discuss
; 232(0): 236-255, 2021 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34545865
6.
Protection from endogenous perforin: glycans and the C terminus regulate exocytic trafficking in cytotoxic lymphocytes.
Immunity
; 34(6): 879-92, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21658975
7.
Perforin-A key (shaped) weapon in the immunological arsenal.
Semin Cell Dev Biol
; 72: 117-123, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757431
8.
Regulation of perforin activation and pre-synaptic toxicity through C-terminal glycosylation.
EMBO Rep
; 18(10): 1775-1785, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28808112
9.
The molecular basis for perforin oligomerization and transmembrane pore assembly.
Immunity
; 30(5): 684-95, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19446473
10.
Conformational changes during pore formation by the perforin-related protein pleurotolysin.
PLoS Biol
; 13(2): e1002049, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25654333
11.
Prevalence and disease predisposition of p.A91V perforin in an aged population of European ancestry.
Blood
; 135(8): 582-584, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31932842
12.
Perforin-mediated target-cell death and immune homeostasis.
Nat Rev Immunol
; 6(12): 940-52, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17124515
13.
Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
J Biol Chem
; 290(42): 25213-26, 2015 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26306037
14.
A Multiantigenic DNA Vaccine That Induces Broad Hepatitis C Virus-Specific T-Cell Responses in Mice.
J Virol
; 89(15): 7991-8002, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26018154
15.
A method for detecting intracellular perforin in mouse lymphocytes.
J Immunol
; 193(11): 5744-50, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25348626
16.
The structural basis for membrane binding and pore formation by lymphocyte perforin.
Nature
; 468(7322): 447-51, 2010 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21037563
17.
Recovery of natural killer cell cytotoxicity in a p.A91V perforin homozygous patient following severe haemophagocytic lymphohistiocytosis.
Br J Haematol
; 190(3): 458-461, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342501
18.
Heterozygosity for the common perforin mutation, p.A91V, impairs the cytotoxicity of primary natural killer cells from healthy individuals.
Immunol Cell Biol
; 93(6): 575-80, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25776844
19.
Adaptive reprogramming of NK cells in X-linked lymphoproliferative syndrome.
Blood
; 131(6): 699-702, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233820
20.
Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack.
Blood
; 121(14): 2659-68, 2013 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23377437